It happened in the northbound lanes at 4:45 a.m. Wednesday near Exit 47 for Route 541.
Police tell Action News the big rig was transporting 80,000 lbs. of packaged apple juice when the driver lost control
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Images from Chopper 6 HD broadcast live on Action News at 6:00 a.m. showed the truck lying on its side across 2 lanes of the 3-lane highway.
The side of the trailer was split open, and boxes of cargo had spilled out onto the road.
Action News is told the driver was injured and transported to an area hospital.
There was no immediate word on that person's condition.
One lane of vehicles was squeezing by in the left shoulder.
Traffic was backed up for miles approaching the scene.
Stay with Action News and 6abc.com for more information as it becomes available.