It happened at 11:30 p.m. Friday in the 5500 block of Lansdowne Avenue.
Authorities say there was a confrontation between two men inside a Chinese restaurant.
The 27-year old victim walked away.
Police say the gunman followed him on foot, pulled a gun and shot him in the neck.
The victim was taken to the Hospital of the University of Pennsylvania, where he died a short time later.
Police are searching for the gunman.