It happened around 11:30 a.m. on the 6600 block of Easton Road (Route 611) in Bedminster Twp.
Police say the two victims were inside their car when it crashed into an unoccupied parked vehicle and then went up in flames.
Further details on the crash are still under investigation, police said.
A nearby building was also damaged after it was struck by one of the vehicles.
The victims have not been identified.
No other injuries were reported.
Anyone who may have witnessed this accident is urged to contact the Bedminster Township Police Department at 215-795-2972.