The incident occurred around 9:30 a.m. at the intersection of Route 141 and Childrens Drive in Talleyville.
Police say there was a multiple vehicle accident at that scene.
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One of the vehicles involved the crash ended up several blocks away, striking bushes and traffic signs along the way.
The vehicle ended up crossing Rockland Road and crashing into a concrete wall at the entrance to Alfred I duPont Hospital for Children.
The male driver of the vehicle was flown to Christiana Hospital.
His condition is not known.
No other injuries from the multi-vehicle crash have been reported.