Mayor Cherelle Parker unveiled the lineup on Thursday for the annual concert on the Ben Franklin Parkway.
The show will be called "One Philly: Unity Concert for America".
Headliners include: Christina Aguilera, Will Smith and DJ Jazzy Jeff, Jill Scott, The Roots, Seal and many more.
Comedian Wanda Sykes will host the event.
The annual concert is free and open to the public.
The show will culminate at midnight with a fireworks finale over the Philadelphia Museum of Art.