Both directions of the highway were impacted by a crash that happened just before 6:30 a.m. in the area of the 12th Street overpass.
Video from Chopper 6 shows damaged vehicles in both the northbound and southbound directions.
Police say the crash involved three vehicles, including a tractor-trailer. The two passenger cars rolled over during the crash, officials said.
New Castle County paramedics say they rescued a 37-year-old driver from his vehicle. He was taken to the hospital in stable condition.
The crashes remain under investigation.