The blaze started before 2 a.m. Friday on the unit block of Francis Street.
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Firefighters responded to reports of people trapped.
VIDEO: Elderly woman perishes in Burlington Co. house fire
They got the blaze under control and found a woman, believed to be in her 80s, who was not able to make it out of the home.
Preliminary reports indicate the fire started accidentally in the living room.
Police and the Burlington County fire marshal are investigating.