The incident occurred around 6 p.m. on the 6100 block of Sauterne Drive in Lower Macungie Twp.
The SUV crashed through a wall and came to rest inside the home.
A person who was sleeping in a room at the time was able to escape safely, according to officials.
The driver was taken to a hospital for treatment.
Authorities are investigating what caused the driver to lose control of the vehicle.