The fire started around 5 p.m. Saturday in the 5000 block of Tacoma Street.
When firefighters arrived, there were reports that someone was trapped inside the home.
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They were able to pull the man out.
Fire Commissioner Adam Thiel even tweeted saying it was a great rescue.
The man was taken to Temple University Hospital for smoke inhalation and second-degree burns. No word on his condition at this time.
Officials say the fire was placed under control within 20 minutes.
The cause of the fire is under investigation.