The crash happened around 10:30 a.m. on Thursday in the northbound lanes of I-495 over the Christina River.
It involved a tanker truck and a pickup truck.
The view from Chopper 6 showed the front end of a truck wedged underneath the tanker.
There has been no word on how the crash happened.
The driver of the truck and the tanker were not hurt. A 14-year-old passenger in the pickup suffered minor facial injuries.