The transit agency is rolling out Phase One of its new bus network, both Sunday and Monday.
It includes new, modified and discontinued routes across the region.
Discontinued routes include the 35, 47M, 62, 78, 80, 89 and 106.
Two new routes are being added, including the 72, which will connect the Frankford Transportation Center to Cedarbrook Plaza.
The second, route 76, will serve North and South Philadelphia.
Five routes are being extended.
Two major changes include the 45 extension, which will now provide 7-day service to the Navy Yard.
The 79 extension will run between South and West Philadelphia.
This is the transit agency's first bus system overhaul of this level.