The stabbing occurred around 11:30 p.m. on the 1600 block of South Taney Street.
The victim was stabbed in the arm and taken to the hospital in stable condition.
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So far, there are no arrests or word on a motive.
This was the second stabbing overnight in the Grays Ferry section.
A teen was also stabbed while playing basketball.
Police do not think the two cases are connected.