Police responded to reports of a shooting around 11:50 p.m. Saturday along the 3500 block of F Street.
Upon arrival, police found a 23-year-old man suffering from multiple gunshot wounds.
Officers transported the victim to Temple University Hospital, where he was pronounced dead a short time later.
A second victim was found nearby in the area of G Street and Erie Avenue.
The male was found suffering from a gunshot wound to his back, and was also transported to Temple University Hospital.
He is listed in stable condition.
No arrests have been made as police continue to investigate.