Kyle Irvin, 55, is accused of shooting and killing 48-year-old Rashida Irvin inside an apartment in the 6300 block of Germantown Avenue last Monday night.
Police were flagged down around 6:35 p.m. by a witness who reported hearing gunshots.
When police entered the location, they found Rashida in the bathroom, suffering from multiple gunshot wounds to the torso.
She was pronounced dead a short time later.
Police say Kyle turned himself in to police just after midnight on Wednesday.
He is being charged with murder and related offenses.