It happened just before 10 p.m. in the southbound lanes of Route 13 near Bacon Avenue.
Delaware State Police say the 51-year-old driver of a Dodge Ram truck struck a 71-year-old man from New Castle as he walked into the roadway from the Manor Park Shopping Center.
The victim was pronounced dead at the scene. He has not been identified.
The truck driver was not injured and remained to speak to authorities.
Anyone who witnessed the crash is asked to contact Delaware State Police at (302) 365-8484.
The crash remains under investigation.