Kenneth Tripline, 36, faces murder charges.
The stabbing happened on Tuesday night in the 100 block of South Avenue.
Investigators Tripline kicked in the door of the victim, 28-year-old Elliot Handy, and stabbed him multiple times.
Police believe the two knew each other, but there's no word on a motive.
Bridgeton police say Tripline should be considered armed and dangerous.
Anyone with information is asked to call Bridgeton police at 856-451-0033.