It happened around 4:49 p.m. Monday on Arrott Street at SEPTA's Arrott Transportation Center.
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Police say one man was shot in the chest. He was taken to Temple University Hospital, where he was pronounced dead.
A second victim, identified by police as a man, was shot once in the back and twice in the leg. He was taken to Temple University Hospital in stable condition.
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It's still unclear what sparked the gunfire and no arrests have been made.
Police say a gun was recovered at the scene.
Anyone with information is asked to call police at 215-686-TIPS.
RELATED: Check the 6abc Neighborhood Safety Tracker