Officers received a call around 8:17 a.m. Saturday from the husband about a shooting on the 200 block of Idlewood Way.
When officers arrived to the couple's home, they found both the husband and wife with life-threatening injuries.
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The husband was taken to Inspira Hospital in Woodbury where he was pronounced dead.
The wife was taken to Cooper Medical Center where she was pronounced dead a short time later.
Police have not identified the couple pending notification of relatives.
The incident is being investigated by the Gloucester County Prosecutor's Office and the Deptford Township Police.