The victim was identified Friday as 22-year-old Christian Serrano of Wilmington.
It happened just after 6:30 p.m. Thursday in the 200 block of North Connell Street.
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Police say a male was shot multiple times.
He was pronounced dead at the scene.
Police are trying to determine if the shooting is in retaliation for a shooting earlier in the afternoon.
Anyone with information is asked to contact police at 302-576-3619 or 302-893-5907. Additionally, tips may be left on the Homicide Hotline at 302-576-3939.