The crash involved two vehicles just after 4:30 a.m. near Exit 48 - Ellis Mill Road.
Chopper 6 over overturned semi on Rt 55 SB in Gloucester County
One driver was hospitalized with minor injuries.
Gloucester County HazMat is assisting Glassboro Fire Department with a diesel leak.
The roadway is expected to be closed for several hours, while recovery operations take place.
The southbound on ramp from Ellis Mill Rd. remains open, officials say.
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New Jersey State Police are investigating the accident.