It happened around 12 a.m. Sunday while a party was being held inside a home on the 1600 block of West Ontario Street.
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Police say a 17-year-old male was injured in the shooting.
He was taken to an area hospital and placed in stable condition.
Police say someone at the party got a call to get out of the home right before about 20 gunshots were fired.
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There were roughly 10 teens inside the home, but no other injuries were reported.
No arrests have been made.
Anyone with any information is asked to call police at 215-686-TIPS.