It happened around 5:00 p.m. Saturday on South 12th Street.
Officials say a 12-inch main broke, causing an impact on several properties including the hotel.
Power at the hotel was also out for a short period of time, but has been restored.
Crews worked through the night to repair the water main break.
Police blocked the street during the repair work.
90% of the hotel rooms are filled. Some of the guests took the Loews' offer to move to another hotel, but most decided to stay.