The discovery was made by a homeowner around 6:30 p.m. Sunday at a residence on the 1800 block of South 22nd Street.
Police say a woman in her 30s was discovered unresponsive and partially dressed. Medics pronounced her dead at the scene.
According to investigators, there appears to be no visible trauma to the woman's body, and no drug paraphernalia was found on the scene.
The cause and manner of death will be determined by the medical examiner's office.
Anyone with information is asked to call police at 215-686-TIPS.