The discovery was made by a homeowner around 6:30 p.m. Sunday at a residence on the 1800 block of South 22nd Street.
Police say a woman in her 30s was discovered unresponsive and partially dressed. Medics pronounced her dead at the scene.
According to investigators, there appears to be no visible trauma to the woman's body, and no drug paraphernalia was found on the scene.
They are treating her death as suspicious until the medical examiner can determine how she died.
Anyone with information is asked to call police at 215-686-TIPS.