Authorities responded to reports of a shooting around 9:45 a.m. on the 2500 block of North Front Street.
An adult female was found in the backyard of a property with a gunshot wound to the right side of her neck.
Her identity has not yet been released.
No arrests have been made, and investigators have not determined a motive.
Anyone with information can call or text Philadelphia police at 215-686-TIPS (8477).