Flames charred the upper floor of a home in the 900 block of Broadway in Bethlehem, Pennsylvania.
The fire happened around 1 a.m. Wednesday.
When firefighters arrived, they saw a leg sticking out of the window. They climbed to free that person, but it was too late.
The victim has been identified as 56-year-old Ladell Christie.
The cause of the fire is under investigation.