It happened around 10:40 p.m. Sunday on Route 412 at Park Drive in Nockamixon Township.
Officials said it appears the driver lost control on Route 412 and the car overturned.
The car ended up off the road and in the bushes with the driver pinned inside of the car.
Officials have given no word as to the condition of the driver at this time.
Route 412 will be closed in the area for some time as the investigation continues.