It happened around 6 a.m. in the southbound lanes of Route 42 near Route 168.
The crash blocked all lanes of Route 42 southbound right at the Black Horse Pike (Exit 10 A) for some time.
Southbound traffic on Route 42 was backed up from Lower Landing Road to past Route 168 and northbound traffic was slowed down with a gaper delay.
At least one injury has been reported.