It happened just before midnight on the 1500 block of Pratt Street.
Officers responded to numerous reports of gunfire. They said when they arrived at the scene, they found the 26-year-old man in the street shot once in the head, lying next to a black Nissan that was running. He was pronounced dead at the scene.
Police are reviewing footage from area crime cameras.
So far there is no word on a suspect or a motive.