It happened around 1:30 a.m. on the 1900 block of Page Street.
Police said a gunman fired at least 23 shots into the front of a house that 15 people had rented for a party.
Investigators said a 20-year-old man was shot three times in the chest and twice in the arm. He was taken to Temple University Hospital where he is in critical condition.
There is no word as to a motive for the shooting.
No arrests have been made at this time.