The crash occurred just after 1:30 a.m. Tuesday on Penrose Avenue near 26th Street.
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Authorities say a driver lost control of a vehicle and struck a power line.
The vehicle continued on Penrose Avenue then rolled onto its side before catching on fire.
The crash brought down PECO wires and utility crews were called in.
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The victim was pronounced dead at the scene.
Investigators blocked off the road for hours as they worked to determine what caused the wreck.