It happened around 6:50 p.m. Monday.
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According to authorities, the crash occurred when two cars heading westbound towards Philadelphia appeared to be speeding. One car clipped the other sending it into the eastbound lane, where it struck a Honda Civic head-on.
Two other vehicles were also hit.
The driver of the Civic, Gerardo Francisco Perez Martinez, 35, of Camden, New Jersey, was pronounced dead at the scene.
Five others were taken to the hospital with various injuries, none of which appear to be life-threatening.
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The bridge reopened to traffic around 2:40 a.m. Tuesday.
No arrest or charges have been announced
Anyone with information pertaining to this crash is asked to call Burlington County Central Communications at 609-265-7113, or send an email to tips@co.burlington.nj.us.
The bridge, operated by the Burlington County Bridge Commission, connects the Tacony section of Philadelphia to Palmyra, Burlington County.