Officials say it happened just after 9 p.m. Saturday near a park.
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According to police, there was a large gathering at 33rd and Reed streets.
Police say a 28-year-old man was shot once in the hip, he was transported to Penn Presbyterian Medical Center and placed in stable condition.
The 32-year-old woman with special needs was shot twice in the stomach, she was also transported to Penn Presbyterian Medical Center and placed in stable condition.
A 35-year-old man was also shot once in each thigh.
Officers say he was also transported to Penn Presbyterian Medical Center and placed in stable condition.
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Police are not sure if the two men shot were targeted, but stated that the woman was just a bystander.
Officers are now trying to gather surveillance video in hopes of catching the shooters.
RELATED: Check the 6abc Neighborhood Safety Tracker