Students were alerted to the incident after the victim notified officials on Tuesday
The assault reportedly took place in an on-campus residence hall room early Sunday morning.
Villanova says the alleged attacker is also a student.
"Villanova University does not tolerate sexual assault or sexual violence in any form. Sexual assault is a violation of University policy, Pennsylvania law, and federal Title IX regulations. It is also a violation of our sense of community and care for one another," said the university in a safety alert.
No other information is being released at this time.