It unfolded in the 6200 block of Market Street in West Philadelphia at 11:30 p.m. Saturday.
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Officers found a woman who had been shot multiple times, lying next to a gun.
She died at the hospital.
Police say there was another woman at the scene who had a gun, and she's now being questioned by homicide detectives.
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Meanwhile, an eyewitness tells Action News that a third person, who is the victim's friend, tried to follow the first responders to the hospital, but ended up in a crash.
The woman who crashed is okay.
Police say the person they're questioning in the shooting did have a permit to carry.