According to investigators, the woman, who is in her 30s, was shot at about 2:30 a.m., outside of a bar near North 56th Street and Wyalusing Avenue.
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The woman told police she had been shot by a man who then ran away.
She was taken to Penn Presbyterian Medical Center where she was listed in critical condition.
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Police said the woman was not cooperating with the investigation. No arrests have been made in connection with the shooting.