"Just to get that little connection with the community and look out your window and see a light, it means a lot to our families right now," explained Sara Narimanian, the child life program coordinator at Nemours.
Light in a time when they need it most. The DeSantis family knows firsthand what this means to the kids.
"Our daughter had an illness called Neutropenia. We spent really the first year of her life here," said Dyani DeSantis of Wilmington.
DeSantis' daughter said she would be waving to all the kids who were inside the hospital.
Dozens of cars, Jeeps, police vehicles, fire trucks and many more took part.
"It's good for the kids that are in that hospital right now, and they may not get home for Christmas. It makes me emotional, I'm sorry," said Maricia Snavely of Wilmington.
The vehicles were all decked out from bumper to bumper. Inflatables and even a real-life waving (and smiling) Grinch all came out to make a difference.
"The nurses say, 'you'll see them crying when we're coming through just because it means someone cares,'" said Narimanian.