Officials said the fire started at about 1:55 a.m. on the unit block of Villanova Court.
The fire department said a 70-year-old victim suffered severe burns and had to be flown to the hospital. Two other people were injured.
One of the people injured escaped through a window of the townhomes, officials said.
The fire severely damaged one townhome. A total of eight people were evacuated from their homes.
The Red Cross is now helping the displaced residents.