Officers in Wilson were called to a home around 10:30 a.m. on the 900 block of South 25th Street for a welfare check.
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At the scene, officials went into the residence, which was made up of two apartments.
In one of the units, officers say they found a 38-year-old woman dead.
There is no word yet on how she died.
They also found a juvenile female who was injured.
The juvenile was taken to the hospital and later transferred to the Children's Hospital of Philadelphia.
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Authorities have not revealed the age or condition of the child.
Police say a male was detained and is also being checked out at the hospital. He is being considered a primary suspect, according to officials.
Wilson police and Northampton County officials have executed a search warrant at the residence and in the hospital.
There is no word yet on whether charges have been filed.