The airline would offer one daily nonstop flight.
At more than 5,700 miles, the Tel Aviv route would be the longest nonstop segment in the US Airways network, and would be served by newer, longer-range Airbus A330-200 aircraft set for delivery in spring 2009.
US Airways began service from Philadelphia to London's Heathrow airport in March 2008.
Philadelphia Mayor Michael Nutter says the airline is working to make its Philadelphia hub a major international gateway.
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