The bus driver was said to be hurt in the collision. However, none of the 10 children on board were injured.
The driver, whose condition has not yet been specified, was taken to Einstein Medical Center along with the driver of the pickup.
The bus driver works with the Leahy Bus Company. The bus serves the Green Woods Charter School.
Initial reports indicate the pickup truck ran a red light. The investigation is continuing.
Click here to get the latest Philadelphia news and headlines from across the Delaware and Lehigh valleys.