The vehicles were stopped, and troopers got consent to conduct a search.
In the one of the vehicles, an SUV driven by Mark Smith of Arizona, police say they found five kilograms of heroin with a street value of $1.6 million.
Smith, and another man in the vehicle who is identified as John Jackson also of Arizona, were arrested and charged with a number of drug violations.
Police found a small amount of marijuana in the other vehicle, a Chevrolet SUV driven by Kyle Johnson of Philadelphia. He was also charged.
Police believe the two vehicles were travelling together.