Investigators with the Collier County Sheriff's Office are looking for the woman's 33-year-old husband, though they have not named him as a suspect.
Sheriff's officials say they want to talk to Mesac Damas, who is a person of interest. He's described as just over six feet tall, 230 pounds, with short black hair and brown eyes.
Authorities say the woman and five young children were found dead inside their home Saturday evening. Investigators have not said how they died or how old they were.