The Nittany Lions (7-1, 3-1 Big Ten) shut down the Wolverines (5-3, 1-3) Saturday after they opened with a 70-yard TD drive.
Clark connected with Zug on the ensuing possession to tie the game. He threw two more TD passes to Zug in the third quarter, giving Penn State a 32-10 lead that it had until taking 10-plus minutes off the clock and kicking a field goal in the fourth.
Michigan struggled to move the ball and had four turnovers.
Tate Forcier was 13 of 30 for 140 yards and an interception. Denard Robinson was 0 for 2 with an interception and fumbled.