It happened between midnight and 6:45 a.m. on Sunday at "Tobacco Zone" at 1023 S. College Avenue.
Police say the suspect seems to have broke in through the front door to steal Newport and Newport 100's cigarettes.
The man was seen in surveillance video wearing a dark, possibly blue, hooded sweatshirt, dark jeans and white sneakers. The man is said to be between 20 and 30 years old, standing about 5'10" to 6'0" tall.
Anyone with information can call Crime Stoppers at 1-800-TIP-3333.
A reward may be available.
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