FDA says Prilosec can block benefits of Plavix

WASHINGTON, D.C.; Novemver 17, 2009

The Food and Drug Administration say the stomach-soothing drug Prilosec lowers the effectiveness of Plavix by half.

Plavix is marketed by Sanofi-Aventis and Bristol-Myers Squibb. It is the world's second-best selling drug with global sales of $8.6 billion last year.

Because Plavix can upset the stomach, it is often prescribed with acid-blocking drugs.

The FDA says patients who need to reduce their stomach acid should take alternative drugs like Johnson & Johnson's Mylanta or Boehringer Ingelheim's Zantac.

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