CBS says the final episode will air next September, in its 54th year. Daytime dramas have been in a long-term ratings decline, and CBS ended the daytime soap "Guiding Light" earlier this year.
Through the years, actors Marisa Tomei, Meg Ryan, Parker Posey and James Earl Jones have appeared on the show.
The cancellation will leave CBS with only two daytime dramas: "The Young and the Restless" and "Bold and Beautiful."
