The "Tonight Show" host and comedian will appear Saturday at the Beau Rivage Theater in Biloxi, Miss., in a benefit performance for residents who've been affected by the massive oil spill.
The appearance is billed as "Stand Up for the Gulf Coast: A Special Evening with Jay Leno to Benefit the Gulf Coast Community Foundation." Leno says the coastal fishing community and others need money, and he wants to help raise it.
Tickets for the benefit are $40, $80 and $150 each.
Funds raised will be administered by the foundation through its Mississippi Oil Spill Recovery Fund.