The "Mad Men" star filed for divorce from Fred Armisen on Monday in Los Angeles.
Her filing cited irreconcilable differences for the breakup.
The two were married in October but separated in June. The court filings did not offer any additional details.
Moss portrays career-oriented Peggy Olson on AMC's Emmy Award-winning "Mad Men." Armisen has appeared on NBC's "Saturday Night Live" since 2002 and parodies President Barack Obama on the show.