"We have stuff that's probably 10 to 15 years old, it's stuff you don't want to throw away the wrong way, you want to make sure the kids don't get to it," Pete Bilinsky of Pennsauken said.
The DEA initiated the prescription drug "Take-Back" campaign last year in New Jersey and today it became a national event.
Prescription drug abuse is second only to marijuana.
4,000 sites across the nation were set up for the "Take-Back" campaign.
In Philadelphia, Bernie Strain recounted the story of his son Tim who was prescribed pain killers for a burned hand.
"[But then] he was still complaining of being in pain from his hand and, tragically, someone gave him additional pain medication from their own medicine cabinet that tragically ended my son's life," Strain said.
Officials call this initiative stop, drop, and roll where one stops by, drops off the drugs and rolls on away, no questions asked.
Bernie Strain asks that everyone look inside their medicine cabinets.
"Maybe it could save, maybe not their son or daughter, but to save one other life," Strain said.
The drugs collected will be incinerated. The DEA says they are drugs that won't wind up in landfills or waterways or in the hands of those who abuse prescription drugs.