The shooting occurred at approximately 9:30 Monday night on the 300 block of Odessa Avenue.
Police were called to the scene where they found 23-year-old Jeffrey Chambers, who had sustained a gunshot wound to his upper torso.
Chambers was rushed to the Christiana Hospital where he later died.
Chambers lived at the location where the shooting took place, according to investigators.
Police had only a vague description of a suspect.
Anyone with information pertaining to the identity or whereabouts of the gunman is asked to contact detectives at 395-8110 or visit www.nccpd.com. You may also provide a text tip at: 847411 (TIP411), begin your message with NCCPD and then type your message. Tipsters may also call Crime Stoppers at (800) TIP-3333.